Bueno Perez, RocioMartin Calvo, AnaGómez-Álvarez, PaulaGutiérrez Sevillano, Juan JoséMerklinga, Patrick J.Vlugtb, Thijs J. H.van Erpc, TitusDubbeldamd, DavidCalero, Sofía2026-01-232026-01-232014Chem. Commun., 2014,50, 10849-1085210.1039/c4cc03745fhttps://hdl.handle.net/10433/25796Spanish Government: CTQ2010-16077 European Research Council (ERC): ERC2011-StG-279520-RASPAThis study reveals the efficient enantiomeric separation of bioactive molecules in the liquid phase. Chiral structure HMOF-1 separates racemicmixtures whereas heteroselectivity is observed for scalemic mixtures of ibuprofen using non-chiral MIL-47 and MIL-53. Lysine enantiomers are only separated by HMOF-1. These separations are controlled by the tight confinement of the molecules.application/pdfenAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Enantioselective adsorptionIbuprofenjournal articleopen access