RT Journal Article T1 Effect of different inter-repetition rest intervals across four load intensities on velocity loss and blood lactate concentration during full squat exercise A1 Mora Custodio, Ricardo A1 Rodríguez Rosell, David A1 Yáñez García, Juan Manuel A1 Sánchez Moreno, Miguel A1 Pareja Blanco, Fernando A1 González Badillo, Juan José K1 Resistance training K1 Fatigue K1 Metabolic stress K1 Cluster configurations AB This study aimed to analyze the acute effect of inter-repetition rest (IRR) intervals on mechanical and metabolic response during four resistance exercise protocols (REPs). Thirty resistance-trained men were randomly assigned to: continuous repetitions (CR), 10 s (IRR10) or 20 s (IRR20) inter-repetition rest. The REPs consisted of 3 sets of 6, 5, 4 and 3 repetitions against 60, 70, 75 and 80% 1RM, respectively, in the full squat exercise. Muscle fatigue was assessed using: percentage of velocity loss over three sets, percentage of velocity loss against the ~1 m·s−1 load (V1 m·s−1), and loss of countermovement jump(CMJ) height pre-post exercise. Blood lactate was measured before and after exercise. The percentage ofvelocity loss over three sets and lactate concentration were significantly lower (P < 0.05) for IRR groups compared to CR in all REPs. The CR group showed a significantly higher (P < 0.05) velocity loss against V1 m·s−1 load and loss of CMJ height pre-post exercise than IRR groups in REP against 60% 1RM. In conclusion, both IRR groups produced a significant lower degree of fatigue compared to CR group. However, no significant differences were found in any measured variables between IRR configurations. PB Taylor and Francis Group YR 2018 FD 2018 LK https://hdl.handle.net/10433/22617 UL https://hdl.handle.net/10433/22617 LA en NO Journal of sports sciences, 36(24), 2856–2864 NO Departamento de Deporte e Informática DS RIO RD May 9, 2026