RT Journal Article T1 Effect of extra virgin olive oil on glycaemia in healthy young subjects. A1 Oliveras-López, María-Jesús A1 Innocenti, Marzia A1 Martín, Franz A1 López García de la Serrana, Herminia A1 Mulinacci, Nadia K1 Extra virgin olive oil K1 Glycaemia K1 Secoiridoids K1 Young subjects AB In this approach we studied the glycaemia levels in 20 healthy young volunteers (26 ± 2 years), before and after a 30-day intake of 50 mL of extra virgin olive oil (EVOO). We selected an oil rich in phenolic compounds (523 mg/L) with a high content of secoiridoidic derivatives (over 94.5%). The findings from our study reveal a significant decrease of glycaemia from 89.6 ± 6.8 to 82.7 ± 10.3 mg/dL (p<0.05), related to a long term daily intake of the study EVOO, as the only added fat. A significant increment of the HDL cholesterol, from 68.7 ± 11.5 to 75.2 ± 4.9 mg/dL, was also highlighted. Total cholesterol, LDL, VLDL, triglycerides, and blood pressure did not show significant variation after the 30-day consumption of this EVOO. So far, few articles have described the influence of EVOO consumption, on plasma glucose levels in humans. This effect is observed in a group of healthy young humans. Moreover, we confirm that the level of free hydroxytyrosol (OH-Tyr) in plasma increased up to fourfold (p<0.05) after the 30-day intake of this EVOO. In addition, the excretion in urine of the main metabolite of OH-Tyr, homovanillic acid (HVA), significantly increased. PB WILEY-VCH YR 2012 FD 2012-04-18 LK https://hdl.handle.net/10433/24912 UL https://hdl.handle.net/10433/24912 LA en NO Oliveras-López, M.-J., Innocenti, M., Martín Bermudo, F., López-García de la Serrana, H. and Mulinacci, N. (2012), Effect of extra virgin olive oil on glycaemia in healthy young subjects. Eur. J. Lipid Sci. Technol., 114: 999-1006. https://doi.org/10.1002/ejlt.201100368 NO Department of Molecular Biology and Biochemistry Engineering, University of Pablo de Olavide of Seville, 41013, Seville, Spain NO Department of Pharmaceutical Science, University of Florence, Sesto Fiorentino (Florence), Italy NO Department of Nutrition and Food Science, University of Granada, 18071, Granada, Spain DS RIO RD May 9, 2026