RT Journal Article
T1 Consumption of extra-virgin olive oil rich in phenolic compounds has beneficial antioxidant effects in healthy human adults.
A1 Oliveras-López, María-Jesús
A1 Berná, Genoveva
A1 Jurado Ruiz, Enrique
A1 López García de la Serrana, Herminia
A1 Martín, Franz
K1 Extra-virgin olive oil
K1 Polyphenols
K1 UPLC–MS
K1 Nutritional intervention
K1 Study Gene expression
K1 Antioxidant enzymes
AB Extra-virgin olive oil (EVOO) possesses beneficial health effects due to its antioxidant activity. In a controlled before-and-after supplementation trial (45 healthy adults), we examined the effects of daily consumption (30 days (d), 50 mL/d) of EVOO rich in phenolic compounds, antioxidant activity and antioxidant enzymes (catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPX)). Participants completed for 30 d a 24-h dietary record. Anthropometric characteristics, body composition, glycemia, plasma lipid profile, plasma polyphenols, total antioxidant capacity, erythrocyte antioxidant enzyme activity, peripheral blood mononuclear cells (PBMC) gene expression were recorded. EVOO supplementation did not modify the first four parameters. Significant increases in plasma antioxidant capacity and antioxidant enzyme activity (CAT, GPX) were observed. Significant increase in SOD and decrease in CAT gene expression were detected. Daily consumption of EVOO rich in phenolic compounds by healthy adults improved their antioxidant status and modified their antioxidant gene expression levels without affecting metabolic parameters.
PB Elsevier
YR 2014
FD 2014-07-09
LK https://hdl.handle.net/10433/25005
UL https://hdl.handle.net/10433/25005
LA en
NO Journal of Functional Foods Volume 10, September 2014, Pages 475-484
NO Department of Molecular Biology and Biochemistry Engineering, Andalusian Center of Molecular Biology and Regenerative Medicine, University Pablo Olavide, Seville, Spain
NO Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Seville, Spain
NO Department of Nutrition and Food Science, School of Pharmacy, University of Granada, Campus Universitario de Cartuja, 18071 Granada, Spain
DS RIO
RD May 6, 2026