RT Journal Article T1 Effect of Acute Intake of Fermented Orange Juice on Fasting and Postprandial Glucose Metabolism, Plasma Lipids and Antioxidant Status in Healthy Human A1 Escudero López, Blanca A1 Cerrillo, Isabel A1 Ortega de la Torre, María de los Ángeles A1 Martín, Franz A1 Fernández-Pachón, María-Soledad K1 Fermented orange juice K1 Acute intake K1 Postprandial K1 Lipids K1 Glucose K1 Antioxidant status K1 Inflammation status K1 Cardiovascular risk K1 Functional food K1 Healthy humans AB Higher postprandial plasma glucose and lipemia, and oxidative and inflammatory responses, are considered important cardiovascular risk factors. Fermentation of fruits has generated products with high concentrations of bioactive compounds. The aim of this study was to evaluate the potential acute effects that fermented orange juice (FOJ) can exert in healthy humans by modulating postprandial response, and inflammatory/antioxidant status, compared with orange juice (OJ). Nine volunteers were recruited for a randomized, controlled, and crossover study. Participants ingested 500 mL of FOJ. At 4 h post intake, subjects consumed a standardized mixed meal. Blood samples were collected at 0–8 h hours post intake. The subjects repeated the protocol with OJ following a 2-week washout period. Glucose and lipid metabolism, plasma antioxidant capacity (ORAC, FRAP), endogenous antioxidants (albumin, bilirubin, uric acid), C-reactive protein and fibrinogen were measured in plasma samples. There was a trend of a smaller increase in LDL-C after FOJ intake compared with OJ, a significant decrease in apo-B and significant increase in ORAC. The glycemic andtriglyceride response of meal was attenuated with FOJ. No differences were obtained in endogenous antioxidants and inflammation status between the treatments. The acute consumption of FOJ could play a protective role against cardiovascular risk factors. PB MDPI YR 2022 FD 2022 LK https://hdl.handle.net/10433/20491 UL https://hdl.handle.net/10433/20491 LA en NO Effect of Acute Intake of Fermented Orange Juice on Fasting and Postprandial Glucose Metabolism, Plasma Lipids and Antioxidant Status in Healthy Human. Foods 2022, 11, 1256. NO This research was funded by the Andalusian Government (project P09-AGR4814M), the PAIDI Program from the Andalusian Government (BIO311) and Spanish Government (project PID2020-116731RB-C21). NO Proyectos de investigaciónFECYT -- Elaboración De Una Novedosa Bebida De Naranja De Baja Graduació...FECYT -- ESTUDIO DE LAS PROPIEDADES FUNCIONALES Y BIOACTIVAS Y DE SUS EF... NO Universidad Pablo de Olavide DS RIO RD May 24, 2026