RT Journal Article T1 Does open innovation always work? The role of complementary assets A1 Carmona-Lavado, Antonio A1 Cuevas Rodríguez, Gloria A1 Cabello-Medina, Carmen A1 Fedriani, Eugenio M. K1 Open innovation K1 R&D K1 Human capital K1 Alliance coordination capabilities K1 Inter-organizational learning capabilities K1 Patenting orientation AB The aim of this research is twofold: first, to identify Open Innovation (OI) configurations, and second, to analyze which configurations are associated with a high, and which with a low, OI performance. Using a configurational approach (involving complementarity and equifinality), we propose that firms use different OI configurations, by combining three openness practices (high number of alliances, partner diversity, and external R&D) and four complementary organizational assets (human capital, alliance coordination capabilities, inter-organizational learning capabilities, and patenting orientation), and that such configurations affect OI performance. We conducted a survey study on the Spanish biotech industry. A sample of 75 companies was analyzed using fuzzy-set qualitative comparative analysis (fsQCA). The results revealed seven high-performing configurations and six low-performing configurations. Configurations combining one or more OI practices and complementary organizational assets achieved a high OI performance, while open configurations lacking the necessary organizational assets were not successful. Closed configurations also performed poorly. The theoretical and managerial implications are discussed. PB Elsevier YR 2021 FD 2021-01 LK https://hdl.handle.net/10433/19624 UL https://hdl.handle.net/10433/19624 LA en NO Carmona-Lavado, A., Cuevas-Rodríguez, G., Cabello-Medina, C., Fedriani, E.M. (2021): Does open innovation always work? The role of complementary assets, Technological Forecasting and Social Change, Volume 162, https://doi.org/10.1016/j.techfore.2020.120316. NO Ministerio de Ciencia y Competitividad (Project ECO2016-78882-R). NO Departamento de Organización de Empresas y Marketing DS RIO RD May 21, 2026