RT Journal Article
T1 Effect of daily intake of a low-alcohol orange beverage on cardiovascular risk factors in hypercholesterolemic humans
A1 Cerrillo, Isabel
A1 Escudero López, Blanca
A1 Ortega de la Torre, María de los Ángeles
A1 Martín, Franz
A1 Fernández-Pachón, María-Soledad
K1 Orange
K1 Bioactive compounds
K1 Alcohol
K1 Cardiovascular risk factor
K1 Lipid profile
K1 Hypercholesterolemic humans
AB Oxidative stress, inflammation status, endothelial dysfunction, and imbalanced lipid metabolism play a major role in cardiovascular disease. Bioactive compounds and moderate alcohol consumption have been associated with decreased cardiovascular risk. This study aimed to evaluate the effect on cardiovascular risk factors of a low-alcohol beverage derived from the alcoholic fermentation of orange juice. Eighteen individuals with moderately high cholesterol levels were randomly assigned to an experimental group (n=9) who drank 500 mL/day of the orange beverage for 2 weeks or a control group (n=9) who drank no orange beverage. Blood samples were drawn at the beginning and end of the study period. Consumption of the beverage significantly decreased plasma levels of total cholesterol (−15.6%), LDL-cholesterol (−17.8%), LDL-cholesterol/HDL-cholesterol ratio (−21.4%), catalase (−25.5%), TBARS (−42.6%), and sVCAM-1 (−5.8%). This orange beverage would have a potential capacity to improve cardiovascular risk in hypercholesterolemic humans, supporting its future consideration as a functional beverage.
PB Elsevier
YR 2019
FD 2019
LK https://hdl.handle.net/10433/20459
UL https://hdl.handle.net/10433/20459
LA en
NO Effect of daily intake of a low-alcohol orange beverage on cardiovascular risk factors in hypercholesterolemic humans. Food Research International 116 (2019) 168-174
NO This work was supported by grants from Project P09-AGR4814M and Grupo PAI BIO311 (Junta de Andalucía).
NO Universidad Pablo de Olavide
DS RIO
RD May 9, 2026