RT Journal Article
T1 Antioxidant Activity and Nutritional Status in Anorexia Nervosa: Effects of Weight Recovery.
A1 Oliveras-López, María-Jesús
A1 Ruiz-Prieto, Inmaculada
A1 Bolaños-Ríos, Patricia
A1 De la Cerda, Francisco
A1 Jáuregui-Lobera, Ignacio
A1 Martín, Franz
K1 Anorexia nervosa
K1 Nutritional status
K1 Diet therapy
K1 Catalase
K1 Total antioxidant capacity
AB Few studies are focused on the antioxidant status and its changes in anorexia nervosa (AN). Based on the hypothesis that renutrition improves that status, the aim was to determine the plasma antioxidant status and the antioxidant enzymes activity at the beginning of a personalized nutritional program (T0) and after recovering normal body mass index (BMI) (T1). The relationship between changes in BMI and biochemical parameters was determined. Nutritional intake, body composition, anthropometric, hematological and biochemical parameters were studied in 25 women with AN (19.20 ± 6.07 years). Plasma antioxidant capacity and antioxidant enzymes activity were measured. Mean time to recover normal weight was 4.1 ± 2.44 months. Energy, macronutrients and micronutrients intake improved. Catalase activity was significantly modified after dietary intake improvement and weight recovery (T0 = 25.04 ± 1.97 vs. T1 = 35.54 ± 2.60μmol/min/mL; p < 0.01). Total antioxidant capacity increased significantly after gaining weight (T0 = 1033.03 ± 34.38 vs. T1 = 1504.61 ± 99.73 μmol/L; p < 0.01). Superoxide dismutase activity decreased (p < 0.05) and glutathione peroxidase did not change. Our results support an association between nutrition improvement and weight gain in patients with AN, followed by an enhancement of antioxidant capacity and catalase antioxidant system.
PB MDPI
YR 2015
FD 2015-03-30
LK https://hdl.handle.net/10433/24890
UL https://hdl.handle.net/10433/24890
LA en
NO Oliveras-López, M.-J.; Ruiz-Prieto, I.; Bolaños-Ríos, P.; De la Cerda, F.; Martín, F.; Jáuregui-Lobera, I. Antioxidant Activity and Nutritional Status in Anorexia Nervosa: Effects of Weight Recovery. Nutrients 2015, 7, 2193-2208. https://doi.org/10.3390/nu7042193
NO Department of Molecular Biology and Biochemical Engineering, University of Pablo de Olavide of Seville, Seville 41013, Spain
NO Behavioral Sciences Institute, Seville 41011, Spain
NO DLCB Laboratory, Seville, 41010, Spain
NO CABIMER, Andalusian Center of Molecular Biology and Regenerative Medicine, University of Pablo de Olavide of Seville, Seville 41013, Spain
DS RIO
RD May 26, 2026