RT Journal Article T1 The associations of pregnancy-related symptoms with health-related quality of life at midpregnancy: the PregnActive project A1 Oviedo Caro, Miguel Ángel A1 Bueno-Antequera, Javier A1 Munguía Izquierdo, Diego K1 Pregnancy K1 Women’s health K1 Nursing K1 Pregnancy symptoms K1 Health-related quality of life AB AimTo analyze the associations between the wide range of pregnancy-related symptoms and health-related quality of life.Material and methodsA cross-sectional study was developed among 155 healthy low-risk pregnant women, aged 18–45 years, participated in the study at midpregnancy. Health-related quality of life and pregnancy symptoms were assessed using the Medical Outcome Study 36-item short form questionnaire and the Pregnancy Symptoms Inventory, respectively. Simple correlations, hierarchical linear regressions and standard multiple regressions were performed.ResultsSignificant correlations, after adjusting for sociodemographic and anthropometric characteristics, were found between five pregnancy-related symptoms and physical component of health-related quality of life and between thirteen pregnancy-related symptoms and mental component. However, when all pregnancy symptoms were entered simultaneously into a multiple regression model, back pain and shortness of breath on the physical components, and feeling depressed and anxiety on the mental component were the main explanatory factors of health-related quality of life.ConclusionAmong the wide range of pregnancy-related symptoms, back pain, hip or pelvic pain, shortness of breath, and feeling depressed and anxiety are the main symptoms affecting the physical and the mental components of health-related quality of life, respectively. An early detection of the pregnancy-related symptoms that may affect health-related quality of life enables early interventions aimed at ameliorating their negative impact on health-related quality of life and daily living activities at midpregnancy. PB Taylor & Francis YR 2022 FD 2022 LK https://hdl.handle.net/10433/27365 UL https://hdl.handle.net/10433/27365 LA en NO Oviedo-Caro, M. A., Bueno-Antequera, J., & Munguía-Izquierdo, D. (2022). The associations of pregnancy-related symptoms with health-related quality of life at midpregnancy: the PregnActive project. The Journal of Maternal-Fetal & Neonatal Medicine, 35(25), 5337–5345. https://doi.org/10.1080/14767058.2021.1879040 NO Universidad Pablo de Olavide. Departamento de Deporte e Informática DS RIO RD Sep 14, 2026