RT Journal Article
T1 BIGO: A web application to analyse gene enrichment analysis results
A1 López Fernández, Aurelio
A1 Rodríguez Baena, Domingo Savio
A1 Gómez-Vela, Francisco Antonio
A1 Díaz-Díaz, Norberto
K1 Gene enrichment analysis
K1 Biclustering
K1 Gene networks
AB Background and objective: Gene enrichment tools enable the analysis of the relationships between genes with biological annotations stored in biological databases. The results obtained by these tools are usually difficult to analyse. Therefore, researchers require new tools with friendly user interfaces available on all types of devices and new methods to make the analysis of the results easier.Methods: In this work, we present the BIGO Web tool. BIGO is a friendly Web tool to perform enrichment analyses of a collection of gene sets. On the basis of the obtained enrichment analysis results, BIGO combines the biological terms to organize them and graphically represents the relationships between gene sets to make the interpretations of the results easier.Results: BIGO offers useful services that provide the opportunity to focus on a concrete subset of results by discarding too general biological terms or to obtain useful knowledge by means of the visual analysis of the functional connections between the sets of genes being analysed.Conclusions: BIGO is a web tool with a novel and modern design that provides the possibility to improve the analysis tasks applied to gene enrichment results.
PB Elsevier
YR 2018
FD 2018-07-04
LK https://hdl.handle.net/10433/25203
UL https://hdl.handle.net/10433/25203
LA en
NO Computational Biology and Chemistry Volume 76, October 2018, Pages 169-178
NO Departamento de Deporte e Informática, Área de Lenguajes y Sistemas Informáticos
DS RIO
RD Apr 23, 2026